Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7484862 | 0.99 | LIPE (0.35) | LIPEEEDNPC1TP53RAB9A | |
| SCHEMBL7476772 | 0.89 | TRPM8 (0.34) | LIPEEEDNPC1TP53RAB9A | |
| SCHEMBL7482587 | 0.83 | GRIN2D (0.37) | LIPEEEDNPC1TP53RAB9A | |
| SCHEMBL7477612 | 0.82 | NAMPT (0.42) | SMN1; SMN2NAMPTHPGDKDM4EALDH1A1 | |
| SCHEMBL7477903 | 0.72 | EED (0.54) | LIPEEEDNPC1TP53RAB9A | |
| SCHEMBL7481285 | 0.71 | SLC6A2 (0.47) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7481472 | 0.70 | GRIN2D (0.34) | LIPEEEDNPC1RAB9AGRIN2D | |
| SCHEMBL7480722 | 0.70 | CYP19A1 (0.41) | NISCH | |
| SCHEMBL7484298 | 0.70 | NAMPT (0.36) | SMN1; SMN2NAMPTROCK2ROCK1GAA | |
| Hydrochloric Acid SCHEMBL7482061 | 0.69 | SLC6A2 (0.46) | EEDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |