SCHEMBL7486559

SCHEMBL7486559

Cc1n[c]c2cn[nH]c2n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1344199 0.76 NOS1 (0.33)
SCHEMBL7492334 0.71 XDH (0.36)
SCHEMBL18493465 0.68 MAPK1 (0.35) MAPK1
SCHEMBL3181459 0.66 PDK2 (0.38) MAPK1MAPT
SCHEMBL7487251 0.64
SCHEMBL7888421 0.63 CHEK1 (0.40)
SCHEMBL838113 0.63
SCHEMBL24348563 0.60 ALDH1A1 (0.39)
SCHEMBL14294267 0.60 PIK3CD (0.39) MAPT
SCHEMBL166657 0.60 PLK4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116171280-A Casein kinase 1 delta modulators 詹森药业有限公司 2023-05-26 CN disclosed
EP-0915093-B1 AMIDE DERIVATIVES OTSUKA PHARMA CO LTD (JP) 2002-11-27 EP disclosed
US-6166016-A Amide derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-12-26 US disclosed
EP-0915093-A1 AMIDE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1999-05-12 EP disclosed