SCHEMBL74874

SCHEMBL74874

[CH2]CC(C)c1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.57
CYP2D6 P10635 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CYP1A2 P05177 1/20 0.49
TSHR P16473 1/20 0.49
HIF1A Q16665 1/20 0.49
AOC3 Q16853 2/20 0.45
ATM Q13315 1/20 0.44
ABCB11 O95342 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 3/20 0.42
SLC6A3 Q01959 3/20 0.42
CYP3A4 P08684 2/20 0.42
KCNH2 Q12809 2/20 0.42
MMP9 P14780 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7496240 0.85 UGT2B7 (0.53) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL7502070 0.82 UGT2B7 (0.50) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL16684715 0.82 UGT2B7 (0.59) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL5401290 0.82 UGT2B7 (0.59) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL30717250 0.80 TAAR1 (0.57) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL6678170 0.80 ABCB11 (0.66) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL6678168 0.80 UGT2B7 (0.57) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL1984485 0.80 TAAR1 (0.57) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL13646401 0.80 UGT2B7 (0.57) UGT2B7CYP2D6MEN1KMT2ACYP1A2
SCHEMBL2096230 0.79 UGT2B7 (0.52) UGT2B7CYP2D6MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238460-A1 IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF TELIX PHARMACEUTICALS INNOVATIONS PTY LTD (AU) 2024-07-18 US disclosed
CN-118339204-A Dual catalyst composition 道达尔能源一技术比利时公司 2024-07-12 CN disclosed
CN-118339205-A Polymerization process using dual catalyst composition 道达尔能源一技术比利时公司 2024-07-12 CN disclosed
CN-118317983-A Dual catalyst composition 道达尔能源一技术比利时公司 2024-07-09 CN disclosed
US-20240216291-A1 Nucleic Acid Containing Nanoparticles BIO TRIP B V (NL) 2024-07-04 US disclosed
US-20240209195-A1 PROCESS TO PRODUCE AN ADDITIVED COMPOSITION OF POLYETHYLENE COMPRISING POST-CONSUMER RESIN AND CAPS OR CLOSURES MADE FROM THIS COMPOSITION TOTALENERGIES ONETECH BELGIUM (BE) 2024-06-27 US disclosed
US-20240209127-A1 NEW METALLOCENE CATALYST AND USE THEREOF TOTALENERGIES ONETECH BELGIUM (BE) 2024-06-27 US disclosed
EP-3110537-B1 USE OF INORGANIC MEMBRANES GRAFTED WITH ORGANIC MOIETIES FOR INCREASING FOULING RESISTANCE VITO NV (BE) 2024-06-12 EP disclosed
EP-4358936-A1 NUCLEIC ACID CONTAINING NANOPARTICLES Bio-TRIP B.V. (NL) 2024-05-01 EP disclosed
EP-4347667-A1 NEW METALLOCENE CATALYST AND USE THEREOF TotalEnergies OneTech Belgium (BE) 2024-04-10 EP disclosed
EP-0757985-A1 N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1997-02-12 EP disclosed
EP-0749966-A1 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-12-27 EP disclosed
EP-0733364-A1 MEDICINAL COMPOSITION FOR CIRCULATORY ORGAN NIPPON SHINYAKU COMPANY, LIMITED (JP) 1996-09-25 EP disclosed
CN-1105354-A Novel alkamine derivative and slat of same YAMANOUCHI PHARMA CO LTD (JP) 1995-07-19 CN disclosed
CN-1051178-A New heterogeneous ring compound and preparation method thereof YAMANOUCHI PHARMA CO LTD (JP) 1991-05-08 CN disclosed
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed
US-4987132-A PLATELET ACTIVATING FACTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 CN disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 EP disclosed
US-4104036-A TO IMPROVE OCTANE RATING ATLANTIC RICHFIELD COMPANY (US) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238460-A1 IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF KLK3, FOLH1, CA14 UGT2B7 3715/4885CYP2D6 4205/4885MEN1 81/4885
US-20240216291-A1 Nucleic Acid Containing Nanoparticles APOB, APOL1, TLR3 UGT2B7 4592/4885CYP2D6 4426/4885MEN1 3590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.