Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 8/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648771 | 0.75 | ACSS2 (0.49) | ACSS2 | |
| SCHEMBL4223848 | 0.72 | ACSS2 (0.51) | ACSS2 | |
| SCHEMBL7490565 | 0.71 | PIN1 (0.41) | PIN1ACSS2 | |
| SCHEMBL7489855 | 0.71 | PIN1 (0.46) | PIN1ACSS2 | |
| SCHEMBL7486158 | 0.71 | ACSS2 (0.38) | PIN1ACSS2 | |
| SCHEMBL3656285 | 0.71 | FGFR1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL7478353 | 0.71 | PIN1 (0.45) | PIN1ACSS2 | |
| SCHEMBL7482199 | 0.70 | PIN1 (0.38) | PIN1ACSS2 | |
| SCHEMBL7485438 | 0.70 | PIN1 (0.37) | PIN1ACSS2 | |
| SCHEMBL7421962 | 0.70 | PIN1 (0.35) | PIN1ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |