Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 13/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348271 | 0.83 | SORD (0.64) | SORDLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6415372 | 0.80 | SORD (0.46) | SORDLMNAKDM4ENPC1RAB9A | |
| SCHEMBL6406954 | 0.66 | LMNA (0.33) | SORDLMNAKDM4ENPC1RAB9A | |
| SCHEMBL6293147 | 0.62 | SORD (0.70) | SORD | |
| SCHEMBL1746338 | 0.62 | — | — | |
| SCHEMBL14641243 | 0.59 | MAPK1 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2PIK3CA | |
| SCHEMBL28618636 | 0.59 | LMNA (0.71) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9052997 | 0.58 | MAPT (0.44) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28710773 | 0.55 | HRH1 (0.61) | KDM4ESMN1; SMN2 | |
| SCHEMBL2721148 | 0.55 | ALDH1A1 (0.49) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1247809-A2 | Triazine compounds useful as sorbitol dehydrogenase inhibitors | Pfizer Products Inc. (US) | 2002-10-09 | — | — | EP | disclosed |