Sugi Predict

Sugi Predict / Compounds / SCHEMBL7488174

SCHEMBL7488174

SCHEMBL7488174

CC(=O)CCC(=O)N1CCN(c2ccc(N3CC(CNC(C)=O)OC3=O)cc2F)CC1

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 7/20 0.74
▸ MAOA P21397 5/20 0.74
▸ PTGS1 P23219 2/20 0.74
▸ SDHA P31040 2/20 0.74
▸ LMNA P02545 1/20 0.74
▸ CALML3 P27482 1/20 0.74
▸ F10 P00742 7/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26771983 0.91 MAOB (0.71) MAOBMAOAPTGS1SDHALMNA
Eperezolid SCHEMBL1176950 0.91 MAOB (0.76) MAOBMAOAPTGS1SDHALMNA
Eperezolid SCHEMBL29421647 0.91 MAOB (0.76) MAOBMAOAPTGS1SDHALMNA
Eperezolid SCHEMBL186562 0.91 MAOB (0.76) MAOBMAOAPTGS1SDHALMNA
SCHEMBL8303747 0.91 MAOA (0.66) MAOBMAOAPTGS1SDHALMNA
SCHEMBL14344848 0.90 MAOB (0.75) MAOBMAOAPTGS1SDHALMNA
Eperezolid SCHEMBL5325217 0.90 MAOB (0.75) MAOBMAOAPTGS1SDHALMNA
SCHEMBL21564243 0.90 MAOB (0.75) MAOBMAOAPTGS1SDHALMNA
SCHEMBL20990014 0.90 MAOB (0.75) MAOBMAOAPTGS1SDHALMNA
SCHEMBL14344988 0.90 MAOB (0.75) MAOBMAOAPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640077-B1 OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS UPJOHN CO (US) 2002-06-26 — — EP claimed