Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 10/20 | 0.43 |
| ▸ | RXRA | P19793 | 9/20 | 0.43 |
| ▸ | RXRB | P28702 | 8/20 | 0.43 |
| ▸ | RXRG | P48443 | 5/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | C5 | P01031 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthol SCHEMBL27476529 | 0.87 | TRPA1 (0.38) | TRPA1TRPV1SLC6A5NR4A2RXRA | |
| SCHEMBL7489192 | 0.84 | PTGIR (0.51) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL7485549 | 0.82 | PTGIR (0.49) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL7481416 | 0.80 | PTGIR (0.38) | TRPA1TRPV1NR4A2RXRARXRB | |
| SCHEMBL7482323 | 0.77 | TAS1R3 (0.37) | SLC6A5NR4A2RXRARXRBRXRG | |
| SCHEMBL7493698 | 0.76 | SIGMAR1 (0.46) | KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7493142 | 0.74 | PTGIR (0.53) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL7493344 | 0.74 | PTGIR (0.53) | NR4A2RXRARXRBRXRGNR4A1 | |
| Hydrochloric Acid SCHEMBL11717772 | 0.74 | NR4A2 (0.51) | TRPA1TRPV1NR4A2RXRARXRB | |
| SCHEMBL27388672 | 0.74 | RXRA (0.39) | NR4A2RXRARXRBRXRGNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-B1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1213285-A2 | 4,5-dipheny-oxazole derivatives and their use as platelet aggregation inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6300344-B1 | FOR THERAPEUTIC AND/OR PROPHYLACTIC TREATMENT OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003973-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |