Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488831 | 0.83 | ADORA2A (0.44) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7489441 | 0.82 | YTHDC1 (0.41) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7492336 | 0.79 | PDE4A (0.39) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7488243 | 0.78 | ADORA2B (0.40) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7492011 | 0.77 | CYP19A1 (0.40) | YTHDC1ADORA2BSMN1; SMN2RXFP1 | |
| SCHEMBL7489715 | 0.77 | LMNA (0.42) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL5731732 | 0.71 | PDE4A (0.66) | YTHDC1ADORA2BADORA2API4KAPI4K2B | |
| SCHEMBL7488235 | 0.70 | DYRK1A (0.35) | YTHDC1ADORA2BADORA2ACDK1 | |
| SCHEMBL7539186 | 0.69 | TSHR (0.47) | SMN1; SMN2ADORA2ALMNA | |
| SCHEMBL7488843 | 0.68 | CNOT7 (0.43) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |