Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750050 | 0.86 | ADRA1A (0.37) | HTR1AADRA1DADRA1AADRA1BCHRNB2 | |
| SCHEMBL750279 | 0.85 | HTR1A (0.41) | HTR1AADRA1DADRA1AADRA1BCHRM2 | |
| SCHEMBL749002 | 0.84 | HTR1A (0.42) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL751256 | 0.83 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3415742 | 0.82 | HTR1A (0.41) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL749632 | 0.81 | HTR1A (0.39) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3413055 | 0.80 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL749623 | 0.80 | HTR1A (0.38) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL751251 | 0.79 | HTR1A (0.39) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3416217 | 0.79 | HTR1A (0.31) | HTR1AADRA1DADRA1AADRA1BCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152812-B1 | DEGASSING COMPOSITIONS FOR CURABLE COATINGS | TROY TECHNOLOGY CORP INC (US) | 2012-03-21 | — | — | EP | claimed |
| US-7842745-B2 | Degassing compositions for curable coatings | TROY CORPORATION (US) | 2010-11-30 | — | — | US | claimed |
| US-20100204373-A1 | Degassing compositions for curable coatings | TROY CORPORATION | 2010-08-12 | — | — | US | claimed |
| US-7842745-B2 | Degassing compositions for curable coatings | TROY CORPORATION (US) | 2010-11-30 | — | — | US | disclosed |
| US-20100204373-A1 | Degassing compositions for curable coatings | TROY CORPORATION | 2010-08-12 | — | — | US | disclosed |