Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | CLK3 | P49761 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24645772 | 0.86 | MAPT (0.67) | MAPTKDM4ECRBNKCNQ3KCNQ2 | |
| SCHEMBL5238314 | 0.80 | UBE2T (0.48) | MAPTKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL7488327 | 0.80 | GAA (0.59) | KDM4ECRBNMEN1KMT2AGAA | |
| SCHEMBL14456792 | 0.79 | SYK (0.48) | CRBNKCNQ3KCNQ2MAPK7DDB1 | |
| SCHEMBL50482 | 0.79 | MAPT (0.69) | MAPTKDM4EKCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL1743189 | 0.78 | IKBKB (0.48) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5204132 | 0.77 | RAB9A (0.62) | MAPTKDM4ECRBNMEN1KMT2A | |
| SCHEMBL7494810 | 0.77 | ALOX12 (0.47) | KDM4ECRBNMEN1KMT2AGAA | |
| SCHEMBL17541609 | 0.76 | SRC (0.51) | MAPTKDM4EMAPK7ALDH1A1SRC | |
| SCHEMBL5202077 | 0.76 | KCNH2 (0.49) | KDM4EALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243268-A1 | MEDICINAL COMPOSITION | Nippon Shinyaku Co., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-1156045-A1 | AMIDE DERIVATIVES AND DRUG COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |