Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493827 | 0.85 | MAPT (0.49) | ALDH1A1SMN1; SMN2HPGDGAANPC1 | |
| SCHEMBL7488992 | 0.83 | MAPT (0.49) | ALDH1A1SMN1; SMN2HPGDGAAL3MBTL1 | |
| SCHEMBL11801755 | 0.83 | MAPT (0.49) | ALDH1A1SMN1; SMN2HPGDGAAL3MBTL1 | |
| SCHEMBL7496103 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HPGDGAAMAPK10 | |
| SCHEMBL7493937 | 0.75 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL4118522 | 0.74 | MEN1 (0.37) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1MAPT | |
| SCHEMBL7493230 | 0.71 | HDAC3 (0.53) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1DHODH | |
| SCHEMBL7493234 | 0.71 | HDAC3 (0.53) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1DHODH | |
| SCHEMBL465265 | 0.71 | HPGD (0.73) | ALDH1A1SMN1; SMN2HPGDTAS2R38GAA | |
| SCHEMBL2086358 | 0.70 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |