Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491261 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDPPIDMEN1KMT2A | |
| SCHEMBL7493239 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5238428 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5238435 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5238423 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4118522 | 0.77 | MEN1 (0.37) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL11418204 | 0.76 | TSHR (0.47) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11545213 | 0.74 | PLA2G1B (0.49) | MEN1KMT2ASMN1; SMN2GAAPOLB | |
| SCHEMBL7496099 | 0.73 | ALDH1A1 (0.56) | ALDH1A1HPGDMEN1KMT2ATSHR | |
| SCHEMBL7496095 | 0.73 | ALDH1A1 (0.56) | ALDH1A1HPGDMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |