Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 15/20 | 0.37 |
| ▸ | MMP1 | P03956 | 9/20 | 0.37 |
| ▸ | MMP3 | P08254 | 9/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 5/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293171 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MMP7MMP1MMP3MMP2 | |
| SCHEMBL6294427 | 0.75 | MCHR1 (0.40) | — | |
| SCHEMBL6293450 | 0.74 | SORD (0.42) | HSD11B1 | |
| SCHEMBL6293205 | 0.69 | SORD (0.39) | ALDH1A1 | |
| SCHEMBL7489299 | 0.69 | SORD (0.53) | — | |
| SCHEMBL6293393 | 0.69 | SORD (0.42) | HSD11B1 | |
| SCHEMBL6586369 | 0.69 | HRH3 (0.43) | — | |
| SCHEMBL6294566 | 0.67 | SORD (0.39) | ALDH1A1 | |
| SCHEMBL6294479 | 0.67 | SORD (0.46) | — | |
| SCHEMBL6297889 | 0.66 | SORD (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185275-A1 | AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS | Pfizer Products Inc. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000059510-A1 | AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-10-12 | — | — | WO | disclosed |