Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555779 | 0.80 | TNF (0.42) | PPARG | |
| SCHEMBL6555842 | 0.77 | TSHR (0.52) | PPARGSMN1; SMN2 | |
| SCHEMBL6557412 | 0.75 | PDE10A (0.57) | — | |
| SCHEMBL6557988 | 0.74 | L3MBTL1 (0.51) | PPARGSMN1; SMN2 | |
| SCHEMBL6055987 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3487712 | 0.71 | PPARG (0.74) | PPARG | |
| SCHEMBL6557586 | 0.71 | KDM4E (0.52) | PPARGSMN1; SMN2 | |
| SCHEMBL6700252 | 0.71 | PPARA (0.57) | PPARG | |
| SCHEMBL6557322 | 0.71 | KDM4E (0.52) | PPARGSMN1; SMN2 | |
| SCHEMBL7617609 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167357-A1 | ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |