Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324359 | 0.80 | MAPT (0.44) | PKMGBA1MAPTKDM4EMEN1 | |
| SCHEMBL7495888 | 0.79 | DRD4 (0.41) | GRIN2BMEN1KMT2ADRD4CYP1A2 | |
| SCHEMBL7496846 | 0.76 | DRD4 (0.48) | DRD4ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7495142 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2ADRD4CHRM4ALDH1A1 | |
| SCHEMBL7494625 | 0.75 | CCR3 (0.42) | KDM4EKMT2ADRD4NPC1RAB9A | |
| SCHEMBL8330679 | 0.72 | GRIN2B (0.42) | GRIN2BMEN1KMT2ADRD4CYP1A2 | |
| SCHEMBL4324084 | 0.67 | DRD4 (0.51) | PKMKDM4EDRD4CYP1A2CYP3A4 | |
| SCHEMBL8325382 | 0.67 | DRD4 (0.34) | PKMDRD4CNR2 | |
| SCHEMBL8324364 | 0.66 | KMT2A (0.42) | PKMMAPTMEN1KMT2ACHRM4 | |
| SCHEMBL7495139 | 0.66 | DRD4 (0.40) | MAPTKDM4EDRD4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |