Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495134 | 0.80 | PKM (0.35) | MAPTPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8324364 | 0.77 | KMT2A (0.42) | MAPTPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7495142 | 0.68 | ALDH1A1 (0.41) | CYP1A2CYP3A4CYP2C9KMT2AALDH1A1 | |
| SCHEMBL27197955 | 0.68 | ACHE (0.42) | MAPTPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27197957 | 0.68 | ACHE (0.42) | MAPTPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25740910 | 0.67 | CYP1A2 (0.51) | MAPTPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17828047 | 0.67 | CYP1A2 (0.51) | MAPTPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8330451 | 0.67 | ALDH1A1 (0.49) | MAPTPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL19717464 | 0.66 | BCHE (0.61) | CYP1A2CYP3A4CYP2C9KMT2AALDH1A1 | |
| SCHEMBL8330567 | 0.66 | POLB (0.38) | MAPTPOLBCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |