Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326763 | 0.89 | DRD4 (0.41) | DRD4CNR2DRD2DRD3 | |
| SCHEMBL8327693 | 0.89 | DRD4 (0.41) | DRD4CNR2DRD2DRD3 | |
| SCHEMBL8330567 | 0.83 | POLB (0.38) | DRD4PKM | |
| SCHEMBL8325386 | 0.79 | DRD4 (0.40) | DRD4DRD2DRD3 | |
| SCHEMBL8330206 | 0.79 | DRD4 (0.39) | DRD4CNR2DRD2DRD3 | |
| SCHEMBL8324228 | 0.79 | DRD4 (0.41) | DRD4CNR2 | |
| SCHEMBL8330663 | 0.74 | DRD4 (0.38) | DRD4CNR2 | |
| SCHEMBL8327397 | 0.73 | GRIN2B (0.38) | DRD4DRD3 | |
| SCHEMBL8321742 | 0.73 | PKM (0.37) | DRD4PKM | |
| SCHEMBL8327681 | 0.73 | DRD4 (0.41) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |