Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 12/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918487 | 0.95 | GHSR (0.43) | GHSRTACR1 | |
| SCHEMBL7868472 | 0.89 | GHSR (0.40) | GHSR | |
| SCHEMBL8150673 | 0.88 | GHSR (0.57) | GHSRTACR1 | |
| Hydrochloric Acid SCHEMBL8590141 | 0.84 | GHSR (0.38) | GHSR | |
| SCHEMBL7759453 | 0.80 | GHSR (0.51) | GHSRTACR1 | |
| SCHEMBL8469385 | 0.74 | GHSR (0.56) | GHSRTACR1 | |
| SCHEMBL7500323 | 0.73 | GHSR (0.55) | GHSRTACR1 | |
| SCHEMBL16860861 | 0.73 | NOTUM (0.36) | — | |
| SCHEMBL8161727 | 0.73 | GHSR (0.39) | GHSRTACR1TACR2F2CTSK | |
| SCHEMBL16539832 | 0.73 | HTR2C (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027046-A4 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1027046-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999021553-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1999-05-06 | — | — | WO | disclosed |