Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 14/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495162 | 0.95 | GHSR (0.44) | GHSRTACR1 | |
| SCHEMBL7868472 | 0.88 | GHSR (0.40) | GHSR | |
| SCHEMBL8150673 | 0.86 | GHSR (0.57) | GHSRTACR1 | |
| Hydrochloric Acid SCHEMBL8590141 | 0.83 | GHSR (0.38) | GHSR | |
| SCHEMBL7759453 | 0.79 | GHSR (0.51) | GHSRTACR1 | |
| SCHEMBL9391707 | 0.75 | GHSR (0.36) | GHSRMMP1MMP3MMP9 | |
| SCHEMBL8466975 | 0.74 | GHSR (0.39) | GHSRTACR1MMP1MMP3MMP9 | |
| SCHEMBL5015355 | 0.73 | GHSR (0.76) | GHSRTACR1 | |
| SCHEMBL9394623 | 0.73 | GHSR (0.35) | GHSRMMP1MMP3MMP9 | |
| SCHEMBL29440089 | 0.73 | GHSR (0.76) | GHSRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066285-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051595-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1999-10-14 | — | — | WO | disclosed |