SCHEMBL74952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28968874	0.83	MAPT (0.45)	MAPTCYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL28968872	0.81	MAPT (0.42)	MAPTKMT2AMEN1NPC1RAB9A
	SCHEMBL74549	0.80	MAPT (0.44)	MAPTCYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL85794	0.78	MAPT (0.40)	MAPTKMT2AMEN1SMN1; SMN2HTT
	SCHEMBL75128	0.77	MAPT (0.41)	MAPTCYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL12390099	0.75	MAPT (0.38)	MAPTKMT2AMEN1NPC1RAB9A
	SCHEMBL75375	0.75	SRC (0.41)	MAPTSMN1; SMN2SRCALDH1A1POLB
	SCHEMBL8100623	0.75	MAPT (0.44)	MAPTCYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL31132053	0.74	THRB (0.39)	CYP3A4CYP2C9CYP2C19ALDH1A1POLB
	SCHEMBL10040353	0.74	SRC (0.40)	MAPTNPC1RAB9ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.