Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546596 | 0.91 | HDAC1 (0.40) | RORCHDAC1SCN9A | |
| SCHEMBL6841382 | 0.81 | WNT3A (0.41) | RORCHDAC1UCHL1 | |
| SCHEMBL7546593 | 0.74 | HDAC1 (0.36) | HDAC1 | |
| SCHEMBL6841380 | 0.73 | TRPV1 (0.41) | UCHL1 | |
| Hydrochloric Acid SCHEMBL6846415 | 0.72 | ABL1 (0.46) | — | |
| SCHEMBL7228820 | 0.71 | WNT3A (0.43) | — | |
| SCHEMBL6846514 | 0.71 | TSHR (0.42) | HDAC1 | |
| SCHEMBL7228824 | 0.71 | WNT3A (0.42) | — | |
| Hydrochloric Acid SCHEMBL6846420 | 0.68 | RAB9A (0.37) | SCN9A | |
| SCHEMBL6844797 | 0.68 | MET (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252146-A1 | AMIDE COMPOUNDS FOR INHIBITING PROTEIN KINASES | AGOURON PHARMACEUTICALS, INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001053274-A1 | AMIDE COMPOUNDS FOR INHIBITING PROTEIN KINASES | AGOURON PHARMACEUTICALS, INC. (US) | 2001-07-26 | — | — | WO | disclosed |