Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036841 | 0.85 | KDM4E (0.56) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL896579 | 0.78 | MAOA (0.57) | ADORA3KDM4EMAPTHSD17B10NPC1 | |
| SCHEMBL22445080 | 0.76 | MAOA (0.68) | ADORA3KDM4EMAPTHSD17B10NPC1 | |
| SCHEMBL2070375 | 0.76 | ESR1 (0.45) | ADORA3KDM4EMAPTHSD17B10RAB9A | |
| SCHEMBL5084294 | 0.76 | KDM4E (0.50) | ADORA3KDM4EMAPTADORA2AADORA1 | |
| SCHEMBL7496402 | 0.75 | KDM4E (0.48) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL28632938 | 0.75 | CYP3A4 (0.71) | ADORA3KDM4EMAPTADORA2AADORA1 | |
| SCHEMBL27696055 | 0.75 | ADORA3 (0.50) | ADORA3KDM4EMAPTADORA2AADORA1 | |
| SCHEMBL10448806 | 0.75 | KDM4E (0.58) | ADORA3KDM4EMAPTADORA2AADORA1 | |
| SCHEMBL29036855 | 0.74 | KDM4E (0.66) | KDM4EMAPTHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153020-A4 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RES PTY LTD (AU) | 2002-08-21 | — | — | EP | claimed |
| CN-1340048-A | Production of isoflavone derivatives | NOVOGEN RES PTY LTD (AU) | 2002-03-13 | — | — | CN | claimed |
| EP-1153020-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | Novogen Research Pty. Ltd. (AU) | 2001-11-14 | — | — | EP | claimed |
| WO-2000049009-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RESEARCH PTY. LTD. (AU) | 2000-08-24 | — | — | WO | claimed |
| CN-100564370-C | The preparation of isoflavone derivative | NOVOGEN RES PTY LTD (AU) | 2009-12-02 | — | — | CN | disclosed |
| CN-1680358-A | Composition concerned with isoflavone and the similar and therapeutical method | NOVOGEN RES PTY LTD (AU) | 2005-10-12 | — | — | CN | disclosed |
| CN-1372555-A | Compositions and methods of treatment involving isoflavones and analogs thereof | NOVOGEN RES PTY LTD (AU) | 2002-10-02 | — | — | CN | disclosed |
| CN-1340048-A | Production of isoflavone derivatives | NOVOGEN RES PTY LTD (AU) | 2002-03-13 | — | — | CN | disclosed |