Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | FPR1 | P21462 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036841 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL27994815 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL22445080 | 0.77 | MAOA (0.68) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL896578 | 0.77 | KDM4E (0.63) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4849595 | 0.76 | MAOA (0.68) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL12095236 | 0.76 | NMUR2 (0.49) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL5773649 | 0.76 | MAOB (0.49) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL19920964 | 0.75 | ALDH1A1 (0.61) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL7496403 | 0.75 | ADORA3 (0.51) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL8676653 | 0.72 | PTGS2 (0.61) | KDM4EALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153020-A4 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RES PTY LTD (AU) | 2002-08-21 | — | — | EP | claimed |
| EP-1153020-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | Novogen Research Pty. Ltd. (AU) | 2001-11-14 | — | — | EP | claimed |
| WO-2000049009-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RESEARCH PTY. LTD. (AU) | 2000-08-24 | — | — | WO | claimed |