Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934311 | 0.85 | ALDH1A1 (0.44) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL1001259 | 0.83 | ABCG2 (0.60) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL6724444 | 0.83 | CYP3A4 (0.51) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL11244826 | 0.82 | MEN1 (0.52) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL27728665 | 0.82 | MGAM (0.50) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL4287360 | 0.81 | ALDH1A1 (0.55) | MAOAALDH1A1CYP3A4MAPTTP53 | |
| SCHEMBL27696055 | 0.79 | ADORA3 (0.50) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL17237780 | 0.78 | MAOA (0.59) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL7496403 | 0.78 | ADORA3 (0.51) | MAOAALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL27728663 | 0.78 | ABCB1 (0.57) | ALDH1A1KDM4ECYP3A4MAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574489-B | Synthetic method of 3',4', 7-trihydroxyisoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2022-04-29 | — | — | CN | claimed |
| CN-111574490-B | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2022-04-29 | — | — | CN | claimed |
| CN-111560000-B | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2022-04-12 | — | — | CN | claimed |
| CN-111606881-B | Synthesis method of 3',4',5',6,7, 8-hexahydroxy isoflavone and application thereof in antioxidation | 中国人民解放军联勤保障部队第九〇四医院 | 2022-03-11 | — | — | CN | claimed |
| CN-113512018-A | Flavonoid compound and preparation method and application thereof | 合肥工业大学 | 2021-10-19 | — | — | CN | claimed |
| CN-111606881-A | Synthesis method of 3 ', 4 ', 5 ', 6, 7, 8-hexahydroxy isoflavone and application thereof in antioxidation | 中国人民解放军联勤保障部队第九〇四医院 | 2020-09-01 | — | — | CN | claimed |
| CN-111574489-A | Synthesis method of 3 ', 4', 7-trihydroxyisoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-25 | — | — | CN | claimed |
| CN-111574490-A | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-25 | — | — | CN | claimed |
| CN-111560000-A | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-21 | — | — | CN | claimed |
| CN-107163015-B | A kind of isoflavone compound and the preparation method and application thereof that can improve cigarette smoking effect | 云南中烟工业有限责任公司 | 2019-08-09 | — | — | CN | claimed |
| CN-103087027-B | Preparation process of polyhydroxy isoflavone | COLLEGE OF MILITARY PREVENTIVE MEDICINE THIRD MILITARY MEDICAL UNIVERSITY OF PLA | 2014-11-19 | — | — | CN | claimed |
| CN-103030647-B | Method for synthesizing glabridin | SHANDONG ANALYSIS TEST CENTER (CN) | 2014-10-29 | — | — | CN | claimed |
| CN-103087027-A | Preparation process of polyhydroxy isoflavone | MILITARY PREVENTION MEDICAL COLLEGE THIRD MILITARY MEDICAL UNIVERSITY OF PLA | 2013-05-08 | — | — | CN | claimed |
| CN-106134378-B | A kind of preparation method of trihydroxy-isoflavone | 中国人民解放军第三军医大学 | 2013-03-13 | — | — | CN | claimed |
| CN-101456845-B | 4,5-diaryl-2-sulfhydryl miazines compounds and synthetic method thereof and pharmaceutical use | UNIV SHAANXI NORMAL | 2010-11-03 | — | — | CN | claimed |
| CN-101495183-A | Treating muscular disorders and improving muscular function | DSM IP ASSETS BV (NL) | 2009-07-29 | — | — | CN | claimed |
| CN-101456845-A | 4,5-diaryl-2-sulfhydryl miazines compounds and synthetic method thereof and pharmaceutical use | UNIV SHAANXI NORMAL (CN) | 2009-06-17 | — | — | CN | claimed |
| CN-101343253-A | 2-amido-4, 5-diaryl miazines compound, preparation and pharmaceutical use thereof | UNIV SHAANXI NORMAL (CN) | 2009-01-14 | — | — | CN | claimed |
| CN-101020662-A | Compound 3,4-diaryl pyrazole and its prepn and medicinal use | UNIV SHAANXI NORMAL (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-1984648-A | Botanical extract compositions and methods of use | MEDICAL RES AND EDUCATION ASSO (US) | 2007-06-20 | — | — | CN | claimed |