Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 7/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746695 | 0.87 | LPAR1 (0.36) | SLC2A1LPAR1LPAR5GHSRPTGER2 | |
| SCHEMBL751895 | 0.84 | DHODH (0.33) | SIGMAR1 | |
| SCHEMBL748289 | 0.84 | SRC (0.39) | SLC2A1GHSRPTGER2ACHE | |
| SCHEMBL748502 | 0.83 | DHODH (0.33) | — | |
| Hydrochloric Acid SCHEMBL750002 | 0.83 | DHODH (0.33) | SIGMAR1 | |
| SCHEMBL751065 | 0.83 | SRC (0.38) | SLC2A1HDAC1HDAC6ACHE | |
| Hydrochloric Acid SCHEMBL748627 | 0.83 | DHODH (0.33) | — | |
| SCHEMBL749615 | 0.83 | MAPT (0.35) | SLC2A1HDAC1HDAC6 | |
| SCHEMBL750950 | 0.83 | SRC (0.36) | HDAC1HDAC6SIGMAR1 | |
| SCHEMBL746629 | 0.82 | WDR5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |