Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745530 | 0.93 | HDAC1 (0.41) | SRCHDAC6HDAC1SLC13A5ESRRG | |
| SCHEMBL747722 | 0.92 | ESRRG (0.41) | SRCHDAC6HDAC1SLC13A5HIF1A | |
| SCHEMBL750906 | 0.92 | TP53 (0.39) | SRCHDAC6HDAC1SLC13A5HIF1A | |
| SCHEMBL749993 | 0.91 | LPAR1 (0.39) | SRCHDAC6HDAC1SLC13A5HIF1A | |
| SCHEMBL746738 | 0.88 | SRC (0.36) | SRCHDAC6HDAC1SLC13A5HIF1A | |
| SCHEMBL747958 | 0.88 | TP53 (0.38) | SRCSLC13A5HIF1AMEN1KMT2A | |
| SCHEMBL750133 | 0.87 | SRC (0.36) | SRCHDAC6HDAC1SLC13A5HIF1A | |
| SCHEMBL750950 | 0.87 | SRC (0.36) | SRCHDAC6HDAC1SLC13A5HIF1A | |
| SCHEMBL749647 | 0.87 | LMNA (0.39) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL748197 | 0.87 | SRC (0.36) | SRCHDAC6HDAC1SLC13A5HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |