Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 7/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749665 | 0.88 | MAPT (0.42) | SRCNPC1LMNARAB9AKMT2A | |
| SCHEMBL745530 | 0.85 | HDAC1 (0.41) | SRCNPC1RAB9AKMT2AACHE | |
| SCHEMBL750950 | 0.85 | SRC (0.36) | SRCLMNAALDH1A1WDR5 | |
| SCHEMBL748532 | 0.85 | RIPK1 (0.37) | GHSRRIPK1SLC2A1PTGER2PTGES | |
| SCHEMBL746739 | 0.84 | SRC (0.37) | SRCGHSRLMNANPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL751875 | 0.84 | SRC (0.36) | SRCLMNAALDH1A1WDR5 | |
| SCHEMBL749660 | 0.84 | SLC2A1 (0.35) | GHSRSLC2A1PTGER2ACHE | |
| SCHEMBL748197 | 0.83 | SRC (0.36) | SRCLMNAALDH1A1 | |
| SCHEMBL747722 | 0.82 | ESRRG (0.41) | SRCLMNAALDH1A1ACHE | |
| SCHEMBL750906 | 0.82 | TP53 (0.39) | SRCLMNAKMT2ASLC2A1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |