Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864938 | 0.86 | L3MBTL1 (0.41) | L3MBTL1NPSR1ALDH1A1PKMNPC1 | |
| SCHEMBL24993326 | 0.83 | L3MBTL1 (0.49) | L3MBTL1NPSR1ALDH1A1PKMNPC1 | |
| SCHEMBL751443 | 0.82 | BRD4 (0.47) | L3MBTL1NPSR1ALDH1A1NPC1TP53 | |
| SCHEMBL1452596 | 0.81 | L3MBTL1 (0.44) | L3MBTL1NPSR1ALDH1A1PKMNPC1 | |
| SCHEMBL1451468 | 0.81 | L3MBTL1 (0.44) | L3MBTL1NPSR1ALDH1A1PKMNPC1 | |
| SCHEMBL71518 | 0.80 | NPSR1 (0.59) | L3MBTL1NPSR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27736016 | 0.77 | L3MBTL1 (0.41) | L3MBTL1NPSR1ALDH1A1PKMNPC1 | |
| SCHEMBL21358029 | 0.77 | L3MBTL1 (0.41) | L3MBTL1NPSR1ALDH1A1PKMNPC1 | |
| SCHEMBL28065363 | 0.76 | TSHR (0.38) | L3MBTL1NPSR1ALDH1A1PKMNPC1 | |
| SCHEMBL18191250 | 0.76 | L3MBTL1 (0.43) | L3MBTL1NPSR1ALDH1A1PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138978-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIV (US) | 2026-05-21 | — | — | US | disclosed |
| WO-2024086569-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2024086570-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-107531648-B | Herbicidal compounds | 先正达参股股份有限公司 | 2021-07-13 | — | — | CN | disclosed |
| US-10385063-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-20 | — | — | US | disclosed |
| US-10385063-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-20 | — | — | US | disclosed |
| EP-3288924-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-03 | — | — | EP | disclosed |
| EP-3288924-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-03 | — | — | EP | disclosed |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2430028-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385063-B2 | Herbicidal compounds | DDT, DAO, HPD | L3MBTL1 1811/4885NPSR1 3327/4885ALDH1A1 165/4885 |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | DDT, NAT1, DDAH1 | L3MBTL1 1473/4885NPSR1 894/4885ALDH1A1 139/4885 |
| US-20260138978-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | CHRM1, CHRM4, CHRM2 | L3MBTL1 1685/4885NPSR1 374/4885ALDH1A1 1029/4885 |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | DDT, DAO, HPD | L3MBTL1 1856/4885NPSR1 3297/4885ALDH1A1 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.