Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843252 | 0.83 | BRD4 (0.56) | BRD4MAPTTSHRKDM4EALOX15 | |
| SCHEMBL749664 | 0.82 | L3MBTL1 (0.44) | MAPTKDM4EL3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL28226937 | 0.79 | BRD4 (0.49) | BRD4MAPTTSHRKDM4EALOX15 | |
| SCHEMBL26081236 | 0.78 | BRD4 (0.51) | BRD4MAPTTSHRKDM4EALOX15 | |
| SCHEMBL750492 | 0.78 | BRD4 (0.51) | BRD4MAPTTSHRKDM4EALOX15 | |
| SCHEMBL1542171 | 0.77 | TSHR (0.58) | BRD4MAPTTSHRL3MBTL1CYP4F2 | |
| SCHEMBL29570791 | 0.77 | TSHR (0.58) | BRD4MAPTTSHRL3MBTL1CYP4F2 | |
| SCHEMBL14398367 | 0.77 | KDM4E (0.60) | BRD4MAPTTSHRKDM4EALOX15 | |
| SCHEMBL159285 | 0.77 | BRD4 (0.50) | BRD4MAPTTSHRKDM4EALOX15 | |
| SCHEMBL3369457 | 0.76 | BRD4 (0.57) | BRD4MAPTTSHRKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655380-A1 | SUBSTITUTED PYRAZINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| US-20130274109-A1 | Substituted Pyrazines Having Herbicidal Activity | BASF SE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274109-A1 | Substituted Pyrazines Having Herbicidal Activity | BASF SE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274109-A1 | Substituted Pyrazines Having Herbicidal Activity | BASF SE (DE) | 2013-10-17 | — | — | US | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012085265-A1 | SUBSTITUTED PYRAZINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012085265-A1 | SUBSTITUTED PYRAZINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2012-06-28 | — | — | WO | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2430028-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2005100334-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050234065-A1 | Dipeptidyl peptidase-IV inhibitors | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234065-A1 | Dipeptidyl peptidase-IV inhibitors | ALPI, DPP4, SI | BRD4 4559/4885MAPT 2826/4885TSHR 326/4885 |
| US-20130274109-A1 | Substituted Pyrazines Having Herbicidal Activity | DDT, CAT, CYP4Z1 | BRD4 3510/4885MAPT 4167/4885TSHR 2324/4885 |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | DDT, NAT1, DDAH1 | BRD4 2795/4885MAPT 4501/4885TSHR 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.