Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498243 | 0.87 | OPRD1 (0.44) | OPRM1OPRD1SLC6A2SLC6A4KMT2A | |
| SCHEMBL5871033 | 0.87 | OPRD1 (0.44) | OPRM1OPRD1SLC6A2SLC6A4KMT2A | |
| SCHEMBL7503837 | 0.87 | OPRD1 (0.44) | OPRM1OPRD1SLC6A2SLC6A4KMT2A | |
| SCHEMBL5870866 | 0.85 | OPRM1 (0.41) | OPRM1OPRD1SLC6A2SLC6A4TMEM97 | |
| SCHEMBL7501264 | 0.81 | OPRD1 (0.42) | OPRM1OPRD1KMT2A | |
| SCHEMBL5871117 | 0.80 | OPRD1 (0.42) | OPRM1OPRD1 | |
| SCHEMBL5870992 | 0.80 | OPRD1 (0.39) | OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL4839293 | 0.80 | OPRM1 (0.40) | OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL5870837 | 0.78 | OPRM1 (0.40) | OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL7497822 | 0.78 | OPRM1 (0.40) | OPRM1OPRD1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| EP-1187810-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000071518-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2000-11-30 | — | — | WO | disclosed |