Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | GAA | P10253 | 7/20 | 0.67 |
| ▸ | GFER | P55789 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22446309 | 0.82 | KDM4E (0.64) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL7498372 | 0.81 | HTT (0.81) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL16311183 | 0.80 | KDM4E (0.61) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL18538548 | 0.77 | MGLL (0.58) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL774049 | 0.77 | ALDH1A1 (0.58) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL3485977 | 0.77 | ALDH1A1 (0.58) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL28243691 | 0.77 | ALDH1A1 (0.58) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL8406024 | 0.75 | GAA (0.59) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL22426249 | 0.75 | ALDH1A1 (0.77) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL12235536 | 0.75 | KDM4E (0.56) | KDM4ELMNAALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310854-B1 | PROCESS FOR THE MANUFACTURE OF 3-AMINO-1-BENZYL-PYRROLIDINES | BAYER AG (DE) | 1992-05-20 | — | — | EP | disclosed |
| US-4910319-A | Process for preparing 3-amino-1-benzylpyrrolidines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| EP-0310854-A1 | Process for the manufacture of 3-amino-1-benzyl-pyrrolidines | BAYER AG (DE) | 1989-04-12 | — | — | EP | disclosed |