Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6765057 | 0.98 | SIRT6 (0.44) | SIRT6ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL174327 | 0.80 | SIRT6 (0.42) | SIRT6ALDH1A1RAB9ANPC1KMT2A | |
| Hydrochloric Acid SCHEMBL11550657 | 0.79 | MAPT (0.54) | SIRT6ALDH1A1KMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL6769742 | 0.76 | ALDH1A1 (0.42) | SIRT6ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL8286902 | 0.75 | PTAFR (0.46) | ALDH1A1 | |
| SCHEMBL3570180 | 0.74 | KEAP1 (0.40) | ALDH1A1KMT2AMAPT | |
| SCHEMBL6871684 | 0.73 | MAOB (0.38) | — | |
| SCHEMBL122260 | 0.73 | ADORA3 (0.46) | ALDH1A1POLBLMNA | |
| Water SCHEMBL9451270 | 0.73 | PTAFR (0.43) | — | |
| Hydrochloric Acid SCHEMBL6864931 | 0.71 | F10 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1390206-A | Inhibitors of factor Xa | COR THERAPEUTICS INC (US) | 2003-01-08 | — | — | CN | disclosed |
| EP-1216231-A2 | INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019798-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2001-03-22 | — | — | WO | disclosed |