Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757491 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM2BFKBP1AMAPTTDP1 | |
| SCHEMBL2707590 | 0.86 | NPC1 (0.46) | ALDH1A1KDM2BKMT2AL3MBTL1 | |
| SCHEMBL203477 | 0.86 | NPC1 (0.46) | ALDH1A1KDM2BKMT2AL3MBTL1 | |
| SCHEMBL750978 | 0.85 | SRD5A1 (0.47) | ALDH1A1FKBP1AMAPTTDP1KMT2A | |
| SCHEMBL750745 | 0.85 | ALDH1A1 (0.41) | ALDH1A1FKBP1AMAPTTDP1KMT2A | |
| SCHEMBL751808 | 0.85 | ALDH1A1 (0.41) | ALDH1A1FKBP1AMAPTTDP1KMT2A | |
| SCHEMBL12567353 | 0.83 | NPC1 (0.43) | ALDH1A1FKBP1AKMT2AL3MBTL1 | |
| SCHEMBL751497 | 0.83 | ALDH1A1 (0.39) | ALDH1A1FKBP1AMAPTTDP1KMT2A | |
| SCHEMBL12098865 | 0.81 | ELANE (0.43) | ALDH1A1 | |
| SCHEMBL12098863 | 0.81 | ELANE (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |