Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751497 | 0.91 | ALDH1A1 (0.39) | SRD5A1SRD5A2ALDH1A1MAPTTDP1 | |
| SCHEMBL2708764 | 0.87 | UCHL1 (0.45) | SRD5A1SRD5A2ALDH1A1KMT2ANPC1 | |
| SCHEMBL205084 | 0.87 | UCHL1 (0.45) | SRD5A1SRD5A2ALDH1A1KMT2ANPC1 | |
| SCHEMBL749960 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1FKBP1AL3MBTL1 | |
| SCHEMBL2757491 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1FKBP1AL3MBTL1 | |
| SCHEMBL750745 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1FKBP1AL3MBTL1 | |
| SCHEMBL751808 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1FKBP1AL3MBTL1 | |
| SCHEMBL204193 | 0.79 | USP30 (0.42) | ALDH1A1KMT2ANPC1HPGD | |
| SCHEMBL2706884 | 0.79 | USP30 (0.42) | ALDH1A1KMT2ANPC1HPGD | |
| SCHEMBL15848654 | 0.77 | ALDH1A1 (0.50) | ALDH1A1FKBP1AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |