Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707839 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL205797 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2757464 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2757491 | 0.85 | ALDH1A1 (0.44) | ALDH1A1FKBP1AKMT2AL3MBTL1MAPT | |
| SCHEMBL749960 | 0.85 | ALDH1A1 (0.44) | ALDH1A1FKBP1AKMT2AL3MBTL1MAPT | |
| SCHEMBL750745 | 0.84 | ALDH1A1 (0.41) | ALDH1A1FKBP1AKMT2AL3MBTL1MAPT | |
| SCHEMBL750978 | 0.81 | SRD5A1 (0.47) | ALDH1A1FKBP1AKMT2AL3MBTL1MAPT | |
| SCHEMBL9977357 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL751497 | 0.81 | ALDH1A1 (0.39) | ALDH1A1FKBP1AKMT2AL3MBTL1MAPT | |
| SCHEMBL2706749 | 0.80 | MEN1 (0.51) | ALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |