Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070637 | 0.86 | DYRK1A (0.44) | DYRK1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10590224 | 0.84 | DYRK1A (0.43) | DYRK1AMAOAMAOBMAPK14DHODH | |
| SCHEMBL10591199 | 0.83 | PTGS2 (0.46) | DYRK1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9226694 | 0.82 | DYRK1A (0.59) | DYRK1AMAPTALDH1A1HPGDCYP1A2 | |
| SCHEMBL1180416 | 0.79 | KIF11 (0.46) | DYRK1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10589586 | 0.79 | IDO1 (0.42) | DYRK1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7500352 | 0.78 | IDO1 (0.44) | DYRK1AMEN1KMT2AHPGDIDO1 | |
| SCHEMBL1180120 | 0.77 | DYRK1A (0.43) | DYRK1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10590930 | 0.76 | PTGS2 (0.57) | — | |
| SCHEMBL10589530 | 0.76 | VCAM1 (0.42) | DYRK1AMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1026206-C | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for preparation thereof | AMERICAN CYANAMID CO (US) | 1994-10-19 | — | — | CN | disclosed |
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| CN-1039807-A | Desinsection, kill mite, nematocides aryl-pyrrolidine and preparation method thereof | AMERICAN CYANAMID CO (US) | 1990-02-21 | — | — | CN | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |