Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117483 | 0.93 | HRH4 (0.37) | HRH4ADORA3KDM4ERXFP1POLB | |
| SCHEMBL7116489 | 0.90 | RORC (0.39) | RORCHRH4ADORA3KDM4ERXFP1 | |
| SCHEMBL7546795 | 0.81 | CNR1 (0.39) | POLB | |
| SCHEMBL7116100 | 0.58 | SIRT1 (0.45) | KDM4EGAATSHR | |
| SCHEMBL27162828 | 0.57 | AR (0.44) | HRH4 | |
| SCHEMBL20565236 | 0.56 | AR (0.43) | HRH4 | |
| SCHEMBL3375196 | 0.55 | PDE2A (0.40) | KDM4EGAA | |
| SCHEMBL9998340 | 0.54 | MAPT (0.45) | KDM4EGAA | |
| SCHEMBL11866171 | 0.54 | ACHE (0.37) | RORCHRH4POLBAURKAAURKB | |
| SCHEMBL29937168 | 0.54 | CNR2 (0.40) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244629-A2 | QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001046150-A2 | QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |