Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116489 | 0.90 | RORC (0.39) | — | |
| SCHEMBL7116100 | 0.81 | SIRT1 (0.45) | CYP2C9CSF1RLMNA | |
| SCHEMBL7500481 | 0.81 | RORC (0.33) | POLB | |
| SCHEMBL7121201 | 0.75 | ALDH1A1 (0.53) | CNR1CSF1R | |
| SCHEMBL7117483 | 0.72 | HRH4 (0.37) | POLB | |
| SCHEMBL7125974 | 0.65 | SIRT1 (0.44) | CSF1R | |
| SCHEMBL7114302 | 0.65 | SIRT1 (0.44) | CNR1CSF1RPOLB | |
| SCHEMBL7116736 | 0.64 | SIRT1 (0.42) | LMNA | |
| SCHEMBL7115575 | 0.63 | SIRT1 (0.42) | CSF1R | |
| SCHEMBL7116744 | 0.63 | SIRT1 (0.46) | CSF1RLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244629-A2 | QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001046150-A2 | QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |