Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261945 | 1.00 | L3MBTL1 (0.61) | L3MBTL1FKBP1AACHEHRH3SMN1; SMN2 | |
| SCHEMBL2070172 | 0.92 | FKBP1A (0.54) | L3MBTL1FKBP1ASMN1; SMN2KMT2ANPY1R | |
| Hydrochloric Acid SCHEMBL5555279 | 0.87 | FKBP1A (0.54) | L3MBTL1FKBP1ASMN1; SMN2KMT2AGAA | |
| SCHEMBL20304005 | 0.83 | KDM4E (0.47) | HRH3SRCGAA | |
| SCHEMBL9205385 | 0.80 | L3MBTL1 (0.54) | L3MBTL1KMT2ANPY1RAPP | |
| SCHEMBL9740346 | 0.78 | L3MBTL1 (0.51) | L3MBTL1KMT2ANPY1RSRCGAA | |
| SCHEMBL7269112 | 0.78 | L3MBTL1 (1.00) | L3MBTL1ACHEHRH3SMN1; SMN2KMT2A | |
| SCHEMBL1626076 | 0.78 | L3MBTL1 (1.00) | L3MBTL1ACHEHRH3SMN1; SMN2KMT2A | |
| SCHEMBL9212361 | 0.78 | L3MBTL1 (1.00) | L3MBTL1ACHEHRH3SMN1; SMN2KMT2A | |
| SCHEMBL610772 | 0.78 | L3MBTL1 (1.00) | L3MBTL1ACHEHRH3SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| EP-1187810-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001092226-A1 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHOD OF USE THEREOF | SEPRACOR, INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| WO-2000071518-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2000-11-30 | — | — | WO | disclosed |