Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205385 | 0.99 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL5369178 | 0.95 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL27491805 | 0.89 | HDAC1 (0.51) | ALDH1A1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL892946 | 0.89 | HDAC1 (0.51) | ALDH1A1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL2070172 | 0.85 | FKBP1A (0.54) | L3MBTL1ALDH1A1KMT2AMEN1HDAC1 | |
| SCHEMBL6198420 | 0.84 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL20303824 | 0.84 | HRH3 (0.50) | KMT2AMEN1HDAC1HDAC6SRC | |
| SCHEMBL28116468 | 0.81 | CCR8 (0.51) | ALDH1A1KMT2AMEN1APPGAA | |
| Hydrochloric Acid SCHEMBL5555279 | 0.80 | FKBP1A (0.54) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL5361723 | 0.80 | POLB (0.53) | ALDH1A1KMT2APOLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |