Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149892 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL4286973 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11379228 | 0.70 | HSP90AA1 (0.41) | KDM4EALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL11271210 | 0.69 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL9900851 | 0.68 | MAPK1 (0.41) | KDM4EALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL343377 | 0.68 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDPTGS2TDP1 | |
| SCHEMBL10448806 | 0.65 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL2856269 | 0.65 | PKM (0.39) | KDM4EALDH1A1HPGDPTGS2TSHR | |
| SCHEMBL28636154 | 0.63 | MAPT (0.39) | KDM4EALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL14754177 | 0.63 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153020-A4 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RES PTY LTD (AU) | 2002-08-21 | — | — | EP | disclosed |
| EP-1153020-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | Novogen Research Pty. Ltd. (AU) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049009-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RESEARCH PTY. LTD. (AU) | 2000-08-24 | — | — | WO | disclosed |