Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6731066 | 0.95 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7502501 | 0.86 | LTA4H (0.50) | LTA4HSIGMAR1ALDH1A1KMT2ALMNA | |
| SCHEMBL7500095 | 0.84 | HPGD (0.50) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL5397779 | 0.80 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL16428483 | 0.79 | CYP2D6 (0.53) | LTA4HSIGMAR1ALDH1A1KMT2ALMNA | |
| SCHEMBL8164751 | 0.78 | POLB (0.42) | LTA4HPTGS2ALDH1A1KMT2ALMNA | |
| SCHEMBL1986255 | 0.78 | MAPT (0.36) | LTA4HALDH1A1KMT2ASMN1; SMN2HTT | |
| SCHEMBL4322787 | 0.78 | CHRNB4 (0.47) | LTA4HALDH1A1KMT2ALMNA | |
| SCHEMBL14966522 | 0.78 | CHRNB4 (0.47) | LTA4HALDH1A1KMT2ALMNA | |
| SCHEMBL7759793 | 0.77 | HRH3 (0.42) | LTA4HALDH1A1KMT2AHTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763022-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND THIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033723-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND THIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | claimed |