Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494684 | 0.84 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL6225236 | 0.83 | LMNA (0.51) | L3MBTL1ATMALDH1A1HRH3LMNA | |
| SCHEMBL6731066 | 0.82 | SIGMAR1 (0.43) | POLBL3MBTL1ALDH1A1HRH3LMNA | |
| SCHEMBL1986255 | 0.82 | MAPT (0.36) | ALDH1A1HRH3SMN1; SMN2LTA4HSLC6A2 | |
| SCHEMBL14966522 | 0.81 | CHRNB4 (0.47) | ALDH1A1LMNATSHRLTA4HSLC6A2 | |
| SCHEMBL4322787 | 0.81 | CHRNB4 (0.47) | ALDH1A1LMNATSHRLTA4HSLC6A2 | |
| SCHEMBL2213888 | 0.80 | LTA4H (0.36) | ALDH1A1HRH3SMN1; SMN2LTA4HCHRNB4 | |
| SCHEMBL1989353 | 0.80 | LTA4H (0.36) | ALDH1A1SLC6A4HRH3SMN1; SMN2LTA4H | |
| SCHEMBL3160983 | 0.79 | CHRNB4 (0.49) | ALDH1A1HRH3LMNALTA4HSLC6A2 | |
| SCHEMBL5115964 | 0.79 | ALDH1A1 (0.33) | POLBALDH1A1SLC6A4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018056-A | Intermediates and processes for preparing benzo (b) thiophenes | ELI LILLY AND COMPANY (US) | 2000-01-25 | — | — | US | disclosed |