Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034274 | 0.87 | HTT (0.33) | AOC3HTTCYP3A4SMN1; SMN2SLC6A2 | |
| SCHEMBL10098880 | 0.82 | RIPK1 (0.36) | AOC3HTTCYP3A4SMN1; SMN2SLC6A3 | |
| SCHEMBL30014105 | 0.81 | AOC3 (0.38) | AOC3HTTCYP3A4SMN1; SMN2SLC6A2 | |
| SCHEMBL20212163 | 0.78 | SIGMAR1 (0.34) | AOC3HTTCYP3A4SMN1; SMN2PRSS1 | |
| SCHEMBL20212164 | 0.78 | SIGMAR1 (0.34) | AOC3HTTCYP3A4SMN1; SMN2PRSS1 | |
| SCHEMBL7503724 | 0.78 | ALDH1A1 (0.38) | AOC3HTTCYP3A4SMN1; SMN2SLC6A2 | |
| SCHEMBL29083922 | 0.77 | HTT (0.32) | AOC3HTTCYP3A4SMN1; SMN2SLC6A2 | |
| SCHEMBL21644742 | 0.77 | CYP3A4 (0.37) | HTTCYP3A4SMN1; SMN2SIGMAR1 | |
| SCHEMBL21644743 | 0.77 | CYP3A4 (0.37) | HTTCYP3A4SMN1; SMN2SIGMAR1 | |
| SCHEMBL9608883 | 0.77 | TRPA1 (0.34) | AOC3HTTCYP3A4SMN1; SMN2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230250-A2 | AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS | CORIXA CORPORATION (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034617-A2 | AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS | CORIXA CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| EP-0983286-A1 | AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS | CORIXA CORPORATION (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998050399-A1 | AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS | CORIXA CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |