Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640842 | 0.88 | KMT2A (0.64) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7570263 | 0.83 | KCNK3 (0.50) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8800854 | 0.82 | MEN1 (0.58) | KMT2AMEN1SMN1; SMN2TP53POLB | |
| SCHEMBL7493834 | 0.82 | KMT2A (0.65) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7570572 | 0.77 | NAMPT (0.55) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29764989 | 0.77 | RAB9A (1.00) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14637696 | 0.77 | RAB9A (1.00) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7568546 | 0.77 | CHRNB2 (0.62) | KMT2AMEN1GAATP53POLB | |
| SCHEMBL15528360 | 0.76 | HTT (0.60) | KMT2AMEN1RAB9AGAARXFP1 | |
| Hydrochloric Acid SCHEMBL29765136 | 0.76 | RAB9A (0.97) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |