Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501376 | 0.83 | KMT2A (0.63) | KCNK3KCNK9RXFP1KMT2AL3MBTL1 | |
| SCHEMBL249223 | 0.78 | KCNK3 (0.49) | KCNK3KCNK9RXFP1HCRTR1HCRTR2 | |
| SCHEMBL27724673 | 0.76 | RXFP1 (0.58) | KCNK3KCNK9RXFP1PNLIPF2R | |
| SCHEMBL7493834 | 0.76 | KMT2A (0.65) | DHODHKMT2AL3MBTL1MEN1GAA | |
| SCHEMBL5240399 | 0.76 | MEN1 (0.49) | KCNK3KCNK9RXFP1PNLIPF2R | |
| SCHEMBL8801750 | 0.74 | USP2 (0.47) | DHODHKDRKMT2AL3MBTL1MEN1 | |
| SCHEMBL4753755 | 0.74 | KCNK3 (0.72) | KCNK3KCNK9RXFP1PNLIPF2R | |
| SCHEMBL30211340 | 0.74 | KCNK3 (0.72) | KCNK3KCNK9RXFP1PNLIPF2R | |
| SCHEMBL7568546 | 0.74 | CHRNB2 (0.62) | KMT2AL3MBTL1MEN1GAATP53 | |
| SCHEMBL8798493 | 0.73 | USP2 (0.52) | DHODHKDRKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915876-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997049707-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049708-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |