Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.51 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.51 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402715 | 0.88 | PLOD2 (0.53) | PLOD2PLOD3PLOD1F2F10 | |
| SCHEMBL8699411 | 0.80 | F10 (0.48) | F2F10PRSS1ROCK2KMT2A | |
| SCHEMBL7501496 | 0.76 | PLOD2 (0.56) | PLOD2PLOD3PLOD1HSD17B10CYP3A4 | |
| SCHEMBL13702169 | 0.76 | MEN1 (0.62) | PRKD1ALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL13702168 | 0.75 | PRKD1 (0.61) | PLOD2PLOD3PLOD1PRKD1ALDH1A1 | |
| SCHEMBL13702156 | 0.75 | MEN1 (0.60) | PRKD1ALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL7329226 | 0.74 | PLOD2 (0.46) | PLOD2PLOD3PLOD1F2F10 | |
| SCHEMBL13702119 | 0.74 | HDAC4 (0.50) | PLOD2PLOD3PLOD1PRKD1ALDH1A1 | |
| SCHEMBL13702120 | 0.74 | KMO (0.63) | PLOD2PLOD3PLOD1PRKD1ALDH1A1 | |
| SCHEMBL31530474 | 0.73 | KDM4C (0.48) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| US-5556977-A | ANTIAGGLOMERANTS FOR CELLS, ANTICOAGULANTS, ANTIISCHEMIC AGENTS USING PYRIDINYLPIPERAZINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |