Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501506 | 0.80 | PLOD2 (0.51) | F10F2PRSS1ROCK2KDR | |
| SCHEMBL8635423 | 0.78 | F10 (0.52) | F10F2PRSS1ITGB3ITGA2B | |
| SCHEMBL8631458 | 0.78 | HRH3 (0.50) | HRH3MAPK1SMN1; SMN2 | |
| SCHEMBL7402715 | 0.77 | PLOD2 (0.53) | F10F2PRSS1CCR1ROCK2 | |
| SCHEMBL8635359 | 0.75 | PRSS1 (0.51) | PRSS1 | |
| SCHEMBL8633669 | 0.74 | CYP2C9 (0.44) | ITGB3ITGA2BROCK2HRH3MAPK1 | |
| SCHEMBL8637098 | 0.73 | ITGB3 (0.46) | ITGB3ITGA2BHRH3 | |
| SCHEMBL7394753 | 0.72 | F10 (0.48) | F10F2PRSS1CCR1ROCK2 | |
| SCHEMBL8838126 | 0.72 | CYP2C9 (0.51) | ITGB3ITGA2BHRH3SMN1; SMN2MEN1 | |
| SCHEMBL8838165 | 0.72 | CHKA (0.48) | ITGB3ITGA2BHRH3MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |