Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.56 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.56 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402712 | 0.87 | PLOD2 (0.53) | PLOD2PLOD3PLOD1DRD4HSD17B10 | |
| SCHEMBL7501490 | 0.87 | DRD2 (0.56) | DRD2 | |
| SCHEMBL7396565 | 0.81 | SLC2A1 (0.55) | DRD2MAPT | |
| SCHEMBL8635359 | 0.79 | PRSS1 (0.51) | DRD4DRD2 | |
| SCHEMBL7501506 | 0.76 | PLOD2 (0.51) | PLOD2PLOD3PLOD1DRD4HSD17B10 | |
| SCHEMBL9080272 | 0.74 | HRH3 (0.51) | DRD2 | |
| SCHEMBL7900184 | 0.74 | PRSS1 (0.53) | HSD17B10MAPT | |
| SCHEMBL7402715 | 0.74 | PLOD2 (0.53) | PLOD2PLOD3PLOD1HSD17B10MAPT | |
| SCHEMBL7402710 | 0.73 | DRD2 (0.59) | DRD2CYP1A2 | |
| SCHEMBL7397112 | 0.73 | HTR1A (0.54) | DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| US-5556977-A | ANTIAGGLOMERANTS FOR CELLS, ANTICOAGULANTS, ANTIISCHEMIC AGENTS USING PYRIDINYLPIPERAZINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |