Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132841 | 0.80 | CD44 (0.46) | HIF1ACD44HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL8392790 | 0.79 | L3MBTL1 (0.50) | MAPTLMNATAAR1ALDH1A1TDP1 | |
| SCHEMBL6648051 | 0.74 | LOXL2 (0.45) | LMNACD44CYP19A1CYP3A4 | |
| SCHEMBL2356316 | 0.74 | CYP3A4 (0.41) | CD44HSD17B10ALDH1A1CYP3A4HPGD | |
| SCHEMBL102570 | 0.71 | HTR2A (0.50) | CD44CYP3A4HPGD | |
| SCHEMBL10822699 | 0.71 | MAPT (0.41) | HSP90AA1KMT2AMAPTMEN1LMNA | |
| SCHEMBL3482721 | 0.71 | CD44 (0.46) | CD44TAAR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL7041083 | 0.71 | MAPT (0.44) | HSP90AA1KMT2AMAPTMEN1LMNA | |
| SCHEMBL30612271 | 0.71 | CHRNA7 (0.46) | HTTALDH1A1 | |
| SCHEMBL9665011 | 0.71 | CHRNA7 (0.46) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613420-B1 | METHOD FOR SELECTIVELY BINDING A SUBSTRATE TO SORBENTS BY WAY OF AT LEAST BIVALENT BONDS | INSTRACTION GMBH (DE) | 2015-05-13 | — | — | EP | disclosed |
| EP-2429564-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ANTIFUNGAL PEPTIDES | BASF SE (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | INSTRACTION GMBH (DE) | 2011-10-20 | — | — | US | disclosed |
| WO-2010139539-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ANTIFUNGAL PEPTIDES | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |
| US-20090162858-A1 | Orthogonal chemical inducer of dimerization | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2009-06-25 | — | — | US | disclosed |
| US-20060292569-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | INSTRACTION GMBH (DE) | 2006-12-28 | — | — | US | disclosed |
| EP-1641833-A2 | SYSTEM COMPRISING EFFECTORS AND ELASTOMERS MODIFIED BY VARIABLE-VOLUME RECEPTORS, METHOD FOR THE PRODUCTION AND USE THEREOF | instrAction GmbH (DE) | 2006-04-05 | — | — | EP | disclosed |
| EP-1613420-A2 | METHOD FOR SELECTIVELY BINDING A SUBSTRATE TO SORBENTS BY WAY OF AT LEAST BIVALENT BONDS | instrAction GmbH (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2005003179-A2 | SYSTEM COMPRISING EFFECTORS AND ELASTOMERS MODIFIED BY VARIABLE-VOLUME RECEPTORS, METHOD FOR THE PRODUCTION AND USE THEREOF | INSTRACTION GMBH (DE) | 2005-01-13 | — | — | WO | disclosed |
| WO-2004085046-A2 | METHOD FOR SELECTIVELY BINDING A SUBSTRATE TO SORBENTS BY WAY OF AT LEAST BIVALENT BONDS | INSTRACTION GMBH (DE) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004059000-A2 | HIGH-THROUGHPUT SCREENING METHOD FOR IDENTIFYING ACTIVE SUBSTANCES BY MEANS OF CO-CULTIVATION | PHENION GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | disclosed |
| US-6156724-A | Uses of didemnins as immunomodulating agents | PHARMA MAR, S.A. (ES) | 2000-12-05 | — | — | US | disclosed |
| US-5721242-A | ADMINISTERING A SYNERGISTIC COMBINATION OF EPIROPRIM AND DAPSONE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | SPR, ABCG2, SHBG | HSP90AA1 1170/4885KMT2A 2726/4885MAPT 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.